Epitope mapping can reveal how a mAb exerts its functional effects - for instance, by blocking the binding of a ligand or by trapping a protein in a non-functional state.

Specialized methods for mapping of the two different classes of epitopes, using high-throughput or high-resolution methods, have been developed. While different in their detail, all of the …

Epitope mapping is defined as the process used to recognize and characterize the epitopes, or antigenic determinants, on an antigen that interact with antibodies or other molecules of interest.

What is Epitope Mapping? Epitope mapping is a pioneering technology that allows for the identification of the structure and sequence of an epitope. This is the basis of therapeutic …

The six epitope mapping technologies used here can be divided into two groups. HDX, HRF, and XL are structure-based methods while ALN, Peptide Array, and DomX are function (binding) …

Authoritative and up-to-date, Epitope Mapping Protocols, Fourth Edition serves as an ideal resource for scientists from a wide range of fields involved in critical antibody research.

Learn what antibody epitopes are and explore key methods for antibody epitope mapping in drug development, diagnostics, vaccine design, and structural immunology.

Epitope mapping is a technique employed to define the region of an antigen that elicits an immune response, providing crucial insight into the structural architecture of the antigen as …

Jan 1, 2025 · Epitope mapping is a technique employed to define the region of an antigen that elicits an immune response, providing crucial insight into the structural architecture of the …

Sep 25, 2023 · Here, we briefly introduce the principles, advantages, and disadvantages of the latest epitope mapping techniques with examples for viral antigen discovery.